By Robert Preidt
MS is an autoimmune disease by which the physique assaults the insulation round nerves. It's not clear what triggers the assault, however mounting proof suggests micro organism performs a task. Gut bacteria can have an effect on the immune system, and eating regimen influences gut bacteria.
To be taught extra in regards to the interaction of eating regimen, intestine micro organism, the immune system and MS, researchers studied 25 MS sufferers and 24 individuals with out the illness.
"We discovered a variety of intestine micro organism related to MS and severity of incapacity of MS sufferers," mentioned research writer Dr. Yanjiao Zhou, an assistant professor of drugs at UConn Well being Faculty of Medication in Farmington, Conn.
"We additionally discovered elevated autoimmune markers and signature metabolites in MS. However what is actually attention-grabbing is how these methods join with one another, and the way eating regimen is concerned in these connections," Zhou mentioned in a College of Connecticut information launch.
Consuming extra meat, having decrease ranges of sure micro organism within the intestine, and extra of sure immune cells within the blood had been all related to MS, in line with the report printed on-line Jan. 27 within the journal EBioMedicine.
Increased meat consumption, which was discovered within the MS sufferers, was linked with decrease intestine ranges of Bacteroides thetaiotaomicron — a micro organism concerned with digesting carbohydrates from greens.
Increased meat consumption was additionally associated to a rise in T-helper 17 cells within the immune system, and a rise in S-adenosyl-L-methionine (SAM) within the blood.
The researchers mentioned the findings counsel that in individuals with MS, one thing disconnects their intestine micro organism from the immune system, leading to autoimmune assaults on the nervous system. This sequence tends to be related to meat-eating, they advised.
In accordance with research writer Dr. Laura Piccio, "That is the primary research utilizing an built-in method to investigate the interaction between eating regimen, intestine microbiome, the immune system and metabolism" and their contribution to MS improvement. Piccio is an affiliate professor of neurology on the College of Sydney who was beforehand at Washington College Faculty of Medication in St. Louis.
The authors wish to increase their analysis to incorporate extra individuals, together with sufferers with a extra extreme type of MS. The intention is to be taught extra in regards to the interplay of eating regimen, intestine micro organism and the immune system in MS to presumably forestall the illness or ease signs.
For extra on a number of sclerosis, go to the American Academy of Household Physicians.
SOURCE: College of Connecticut, information launch, Jan. 27, 2022